Rodent Brain Pathology, Audiogenic Epilepsy
Open Access
- 8 November 2021
- journal article
- review article
- Published by MDPI AG in Biomedicines
- Vol. 9 (11) , 1641
Abstract
The review presents data which provides evidence for the internal relationship between the stages of rodent audiogenic seizures and post-ictal catalepsy with the general pattern of animal reaction to the dangerous stimuli and/or situation. The wild run stage of audiogenic seizure fit could be regarded as an intense panic reaction, and this view found support in numerous experimental data. The phenomenon of audiogenic epilepsy probably attracted the attention of physiologists as rodents are extremely sensitive to dangerous sound stimuli. The seizure proneness in this group shares common physiological characteristics and depends on animal genotype. This concept could be the new platform for the study of epileptogenesis mechanisms.Keywords
This publication has 113 references indexed in Scilit:
- The Dorsolateral Periaqueductal Gray and Its Role in Mediating Fear Learning to Life Threatening EventsPLOS ONE, 2012
- Seizure susceptibility is associated with altered protein expression of voltage-gated calcium channel subunits in inferior colliculus neurons of the genetically epilepsy-prone ratBrain Research, 2010
- Calcium channel dysfunction in inferior colliculus neurons of the genetically epilepsy-prone ratNeuropharmacology, 2008
- Murine Dishevelled 3 Functions in Redundant Pathways with Dishevelled 1 and 2 in Normal Cardiac Outflow Tract, Cochlea, and Neural Tube DevelopmentPLOS Genetics, 2008
- The loss of circadian PAR bZip transcription factors results in epilepsyGenes & Development, 2004
- Abnormalities in Brain Serotonin Concentration, High‐Affinity Uptake, and Tryptophan Hydroxylase Activity in Severe‐Seizure Genetically Epilepsy‐Prone RatsEpilepsia, 1996
- A genetic, physiological, and biochemical investigation of audiogenic seizures in ratsBehavior Genetics, 1993
- Audiogenic seizure severity and hearing deficits in the genetically epilepsy-prone ratExperimental Neurology, 1990
- Effects of inferior colliculus lesions on the acoustic startle response.Behavioral Neuroscience, 1990
- II. Noradrenergic and serotonergic determinants of seizure susceptibility and severity in genetically epilepsy-prone ratsLife Sciences, 1986