K-Ras4A Plays a More Significant Role than K-Ras4B in Ductal Carcinoma of Breast
Authors:
Open Access
- 1 March 2023
- journal article
- research article
- Published by Apex Publishing in The Payam-e-Marefat-Kabul Education University
- Vol. 27 (2) , 126-135
Abstract
Background: K-Ras mutations rarely occur in breast cancer. However, studies have supported that K-Ras upregulation is involved in breast cancer pathogenesis. Two main K-Ras transcript variants; K-Ras4A and K-Ras4B, originate from the alternative splicing of exon 4. In this study, we aimed to evaluate variations in the expression of K-Ras4A ...Keywords
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