No evidence for a polyomavirus association or aetiology in AIDS-associated nonsmall cell lung cancer
Open Access
- 15 May 2010
- journal article
- Published by Wolters Kluwer Health in AIDS
- Vol. 24 (8) , 1221-1223
Abstract
AIDS-associated lung cancer has an increasing incidence, unaccounted for by smoking, and occurs consistently at a younger age than matched controls. We investigated whether known and new cancer-associated polyomaviruses, including the newly identified Merkel cell virus, may play a role in its etiopathogenesis. Although viruses target conserved pathways in cellular evolution, we are unable to suggest that the viruses studied here induce novel mechanisms of oncogenic dysregulation in AIDS-associated lung cancer.Keywords
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