Enantioselective S−H Insertion Reactions of α‐Carbonyl Sulfoxonium Ylides
Open Access
- 30 April 2020
- journal article
- research article
- Published by Wiley in Angewandte Chemie International Edition
- Vol. 59 (36) , 15554-15559
Abstract
The first example of enantioselective S−H insertion reactions of sulfoxonium ylides is reported. Under the influence of thiourea catalysis, excellent levels of enantiocontrol (up to 95 % ee ) and yields (up to 97 %) are achieved for 31 examples in S−H insertion reactions of aryl thiols and α‐carbonyl sulfoxonium ylides.Keywords
Funding Information
- Foundation for the National Institutes of Health (5 R35 GM124804)
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