Dually degradable click hydrogels for controlled degradation and protein release
- 8 July 2014
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of Materials Chemistry B
- Vol. 2 (34) , 5511-5521
Abstract
Crosslinks that can undergo click bond cleavage and ester hydrolysis were incorporated to design glutathione-sensitive, dually degradable hydrogels for degradation-mediated, controlled release of cargo molecules.Keywords
This publication has 64 references indexed in Scilit:
- Student award for outstanding research winner in the Ph.D. category for the 9th World Biomaterials Congress, Chengdu, China, June 1–5, 2012Journal of Biomedical Materials Research Part A, 2012
- Differential effects of substrate modulus on human vascular endothelial, smooth muscle, and fibroblastic cellsJournal of Biomedical Materials Research Part A, 2012
- Maleimide Cross‐Linked Bioactive PEG Hydrogel Exhibits Improved Reaction Kinetics and Cross‐Linking for Cell Encapsulation and In Situ DeliveryAdvanced Materials, 2011
- Tunable Degradation of Maleimide–Thiol Adducts in Reducing EnvironmentsBioconjugate Chemistry, 2011
- The effect of protein structure on their controlled release from an injectable peptide hydrogelBiomaterials, 2010
- Characterization of protein release from hydrolytically degradable poly(ethylene glycol) hydrogelsBiotechnology and Bioengineering, 2010
- Poly(ethylene glycol) hydrogels formed by thiol-ene photopolymerization for enzyme-responsive protein deliveryBiomaterials, 2009
- DNA delivery from matrix metalloproteinase degradable poly(ethylene glycol) hydrogels to mouse cloned mesenchymal stem cellsBiomaterials, 2009
- Hydrolytically Degradable Hyaluronic Acid Hydrogels with Controlled Temporal StructuresBiomacromolecules, 2008
- Production of heparin-functionalized hydrogels for the development of responsive and controlled growth factor delivery systemsJournal of Controlled Release, 2007