Periorbital Myxedema

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Abstract
A 71-year-old woman with a history of hypothyroidism presented to the emergency department with dyspnea. Physical examination revealed massive lower eyelid edema bilaterally (image) and dry, flaky skin on her lower extremities. Vital signs were normal. Further investigation revealed that the patient had been noncompliant with her prescribed levothyroxine for more than a year. The results of biochemical tests revealed a thyroid-stimulating hormone level of 220 mIU/L and a free thyroxine level of 0.15 µg/dL. The patient was admitted to the hospital, where a 0.1-mg intravenous dose of levothyroxine was administered daily for 3 days.
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