Experimental Models of Abdominal Aortic Aneurysms
Author:
Open Access
- 26 November 2010
- journal article
- Published by Bentham Science Publishers Ltd. in The Open Cardiovascular Medicine Journal
- Vol. 4 (1) , 221-230
Abstract
Despite being a leading cause of death in the West, the pathophysiology of abdominal aortic aneurysms (AAA) is still incompletely understood. Pharmacotherapy to reduce the growth of small AAAs is limited and techniques for repairing aneurysms continue to evolve. Experimental models play a key role in AAA research, as they allow a detailed evaluation of the pathogenesis of disease progression. This review focuses on in vivo experimental models, which have improved our understanding of the potential mechanisms of AAA development and contributed to the advancement of new treatments.Keywords
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