Enantiodiscrimination Using a Chiral Crown Ether as a Chiral Solvating Agent Using NMR Spectroscopy
Authors:
Open Access
- 1 May 2019
- journal article
- research article
- Published by SAGE Publications in Natural Product Communications
- Vol. 14 (5)
Abstract
For enantiomer separation of a variety of chiral compounds, a number of chiral selectors have been developed and applied. Among these chiral selectors are chiral crown ethers, a class of synthetic polyether molecules that bind protonated chiral primary amines with high selectivity. This article focuses on enantiodiscrimination using (18-crown-6)-2,3,11,12-tetracarboxylic acid as a crown ether-type chiral solvating agent for nuclear magnetic resonance spectroscopic method in several chirotechnologies.Keywords
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