BIOCHEMICAL STUDIES OF TOXIC AGENTS. THE METABOLISM OF IODOMETHANE
Authors:
- Ea BarnsleyEBEa Barnsley
- L YoungLYL Young
- 1 April 1965
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 95 (1) , 77-81
Abstract
The metabolism of iodomethane was studied after the administration of the compound to rats by subcutaneous injection. The urinary excretion of S-methylcysteine, methylmercapturic acid, methylthioacetic acid and N-(methylthioacetyl)glycine was demonstrated by paper chromatography. Methylmercapturic acid and N-(methylthioacetyl)glyclne was isolated from the urine of the dosed animals. The methylthio compounds detected represented about 2% of the iodomethane administered.Keywords
This publication has 14 references indexed in Scilit:
- The metabolism of S-methyl-l-cysteine in the ratBiochimica et Biophysica Acta (BBA) - General Subjects, 1964
- Biochemical studies of toxic agents. 15. The biosynthesis of ethylmercapturic acid sulphoxideBiochemical Journal, 1964
- Formation of mercapturic acids. 5. Metabolism of some halogenoparaffins and nitroparaffinsBiochemical Journal, 1964
- A micro-artificial rumen for isotopic experimentsBiochemical Journal, 1964
- Biochemical studies of toxic agents. 14. The biosynthesis of ethylmercapturic acidBiochemical Journal, 1963
- Toxic liver injury and carcinogenesis. Methylation of proteins of rat-liver slices by dimethylnitrosamine in vitroBiochemical Journal, 1962
- The formation of mercapturic acids. 3. N-Acetylation of S-substituted cysteines in the rabbit, rat and guinea pigBiochemical Journal, 1959
- Effects of methyl bromide on phosphorus metabolism in the adult housefly, Musca domestica L.Biochemical Journal, 1958
- The analysis of urinary 17-oxo steroids by gradient elutionBiochemical Journal, 1957
- (+)-(S-Methyl-l-cysteine S-oxide) in cabbageBiochemical Journal, 1956