Near-Drowning Complicated by Brain Abscess due to Petriellidium boydii

Authors:
  • JFJohn F. Fisher
    John F. Fisher
  • SSSmith Shadomy
    Smith Shadomy
  • JTJ. Robert Teabeaut
    J. Robert Teabeaut
  • JWJanet Woodward
    Janet Woodward
  • GMGene E. Michaels
    Gene E. Michaels
  • MNMark A. Newman
    Mark A. Newman
  • EWElizabeth White
    Elizabeth White
  • PCPaul Cook
    Paul Cook
  • ASAnnette Seagraves
    Annette Seagraves
  • FYFarivar Yaghmai
    Farivar Yaghmai
  • JRJ. Peter Rissing
    J. Peter Rissing
Publisher website
Google Scholar
Abstract
• Extracutaneous infection fromPetriellidium boydiiis an unusual occurrence despite the ubiquity of the organism in nature. Central nervous system infection by this organism is extremely rare, only seven previous reports having been found. The rarity of this manifestation prompted the report of a brain abscess occurring in a previously healthy youth after a near-drowning. The source of the infection was likely to have been the river water at the accident site, from whichP boydiiwas isolated. Although previous in vitro susceptibility data and failure of amphotericin B therapy in a similar infection suggested miconazole treatment might be beneficial, the organism causing the brain abscess was resistant to miconazole and amphotericin B. This report emphasizes the urgent need for safer and more predictably effective alternatives to currently available antifungal agents.

This publication has 11 references indexed in Scilit: