Acute myeloid leukemia: advancing clinical trials and promising therapeutics
Authors:
- 17 March 2016
- journal article
- review article
- Published by Taylor & Francis in Expert Review of Hematology
- Vol. 9 (5) , 433-445
Abstract
Recent progress in understanding the biology of acute myeloid leukemia (AML) and the identification of targetable driver mutations, leukemia specific antigens and signal transduction pathways has u...Keywords
Funding Information
- MD Anderson Cancer Centre Leukaemia Support Grant (CA016672)
This publication has 104 references indexed in Scilit:
- Prognostic Relevance of Integrated Genetic Profiling in Acute Myeloid LeukemiaNew England Journal of Medicine, 2012
- Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencingNature, 2012
- Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent DioxygenasesCancer Cell, 2011
- DNA Methylation Signatures Identify Biologically Distinct Subtypes in Acute Myeloid LeukemiaCancer Cell, 2010
- Cancer-associated IDH1 mutations produce 2-hydroxyglutarateNature, 2009
- AC220 is a uniquely potent and selective inhibitor of FLT3 for the treatment of acute myeloid leukemia (AML)Blood, 2009
- Recurring Mutations Found by Sequencing an Acute Myeloid Leukemia GenomeNew England Journal of Medicine, 2009
- IDH1andIDH2Mutations in GliomasNew England Journal of Medicine, 2009
- Genomic Analysis of the Clonal Origins of Relapsed Acute Lymphoblastic LeukemiaScience, 2008
- Sonic hedgehog regulates angiogenesis and myogenesis during post‐natal skeletal muscle regenerationJournal of Cellular and Molecular Medicine, 2008