Isolation, structure and biological activities of platencin A2–A4 from Streptomyces platensis
Authors:
- John OndeykaJOJohn Ondeyka
- Lisa DietrichLDLisa Dietrich
- Francis P. GailliotFGFrancis P. Gailliot
- Michelle HesseMHMichelle Hesse
- Michael LesterMLMichael Lester
- Karen DorsoKDKaren Dorso
- Mary MotylMMMary Motyl
- Sookhee N. HaSHSookhee N. Ha
- Jun WangJWJun Wang
- Sheo B. SinghSSSheo B. Singh
- 1 April 2010
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry
- Vol. 18 (7) , 2602-2610
Abstract
No abstract availableKeywords
This publication has 29 references indexed in Scilit:
- Chemistry of platensimycinTetrahedron Letters, 2007
- Isolation and Structure of Platencin: A FabH and FabF Dual Inhibitor with Potent Broad‐Spectrum Antibiotic ActivityAngewandte Chemie International Edition, 2007
- Asymmetric Total Syntheses of PlatensimycinAngewandte Chemie International Edition, 2007
- An Expedient Enantioselective Strategy for the Oxatetracyclic Core of PlatensimycinOrganic Letters, 2007
- Discovery of platencin, a dual FabF and FabH inhibitor with in vivo antibiotic propertiesProceedings of the National Academy of Sciences, 2007
- Formal Synthesis of (±)-PlatensimycinOrganic Letters, 2007
- Total Synthesis of PlatensimycinAngewandte Chemie International Edition, 2006
- Isolation, Structure, and Absolute Stereochemistry of Platensimycin, A Broad Spectrum Antibiotic Discovered Using an Antisense Differential Sensitivity StrategyJournal of the American Chemical Society, 2006
- Platensimycin is a selective FabF inhibitor with potent antibiotic propertiesNature, 2006
- Discovery of FabH/FabF Inhibitors from Natural ProductsAntimicrobial Agents and Chemotherapy, 2006