Fertility and Ovarian Reserve among Women with Rheumatoid Arthritis

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Abstract
Objective.: We sought to identify causes for infertility in women with and without rheumatoid arthritis (RA).Methods.: Women with RA were matched to healthy controls. Differences in anti-Müllerian hormone (AMH) and anovulation were analyzed.Results.: Women with RA had lower AMH (β −1.05, 95% CI −2.09 to −0.005), but no difference was observed when AMH was log-transformed. No difference in anovulation was observed. Infertility prevalence was similar between groups, primarily attributable to polycystic ovary syndrome in healthy controls but largely unexplained in women with RA.Conclusion.: AMH was lower in women with RA, but reasons for infertility among women with RA remain unknown.

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