Correlation of Ibuprofen Bioavailability with Gastrointestinal Transit by Scintigraphic Monitoring of 171Er-Labeled Sustained-Release Tablets
Authors:
- 1 December 1987
- journal article
- research article
- Published by Springer Nature in Pharmaceutical Research
- Vol. 4 (6) , 486-489
Abstract
External gamma scintigraphy was used to monitor the gastrointestinal (GI) transit of radiolabeled sustained-release tablets containing 800 mg ibuprofen in eight fasted healthy volunteers. Ibuprofen...Keywords
This publication has 7 references indexed in Scilit:
- Radiolabeling of an enteric coated tablet by (n,γ) radioactivation of erbium-170 for scintigraphic imagingInternational Journal of Pharmaceutics, 1986
- Radiolabeling of Intact Tablets by Neutron Activation for In Vivo Scintigraphic StudiesJournal of Pharmaceutical Sciences, 1985
- On the intestinal transit of a single non-disintegrating objectInternational Journal of Pharmaceutics, 1984
- Gastric emptying of enteric-coated tabletsDigestive Diseases and Sciences, 1984
- High-performance liquid chromatographic determination of ibuprofen and its major metabolites in biological fluidsJournal of Chromatography B: Biomedical Sciences and Applications, 1982
- Method for Monitoring Hard Gelatin Capsule Disintegration Times in Humans Using External ScintigraphyJournal of Pharmaceutical Sciences, 1976
- The acute mammalian toxicity of rare earth nitrates and oxidesToxicology and Applied Pharmacology, 1963