Treatment of Dystonia
Authors:
- Jennifer G. GoldmanJGJennifer G. Goldman
- Cynthia L. ComellaCCCynthia L. Comella
- 1 March 2003
- journal article
- review article
- Published by Wolters Kluwer Health in Clinical Neuropharmacology
- Vol. 26 (2) , 102-108
Abstract
Therapeutic strategies in the treatment of dystonia consist primarily of pharmacologic, surgical, and supportive approaches. Many recent advances have been made in the treatment of dystonia with newer medications, availability of different botulinum toxins, and surgical procedures. However, these treatment modalities all have limiting factors and varying levels of efficacy. Studies range from case reports and open-label trials to double-blind placebo-controlled trials. More research and larger studies are needed to explore these newer medications and surgical techniques for both primary focal and generalized dystonia. Studies in functional outcome and quality of life further support the importance of discovering safe and effective means to treat dystonia. An algorithmic approach may be useful to guide the physician along the various treatment choices.Keywords
This publication has 54 references indexed in Scilit:
- Dystonia: clinical features, genetics, and treatmentCurrent Opinion in Neurology, 2002
- The DYT1 phenotype and guidelines for diagnostic testingNeurology, 2000
- DystoniaCurrent Opinion in Neurology, 1998
- The pathophysiology of primary dystoniaBrain, 1998
- The Neurophysiology of DystoniaArchives of Neurology, 1998
- Spread of symptoms in idiopathic torsion dystoniaMovement Disorders, 1995
- Baclofen in the Treatment of DystoniaClinical Neuropharmacology, 1992
- Treatment of movement disorders with trihexyphenidylMovement Disorders, 1989
- Analysis of open‐label trials in torsion dystonia using high dosages of anticholinergics and other drugsMovement Disorders, 1988
- Torsion dystoniaNeurology, 1986