Detection of Hepatitis B Virus-specific DNA in the Genomes of Human Hepatocellular Carcinoma and Liver Cirrhosis Tissues
Authors:
- R. KoshyRKR. Koshy
- Ph. MaupasPMPh. Maupas
- R. MullerRMR. Muller
- P. H. HofschneiderPHP. H. Hofschneider
- 1 November 1981
- journal article
- research article
- Published by Microbiology Society in Journal of General Virology
- Vol. 57 (1) , 95-102
Abstract
Summary Hepatitis B virus-related DNA was detected in the chromosomal DNA of three out of seven hepatocellular carcinomas and two out of five cirrhosis samples examined, by means of the blot-hybridization technique, described by Southern (1975). The integration patterns were not identical but some similarities raise the question of whether there are some preferred sites of viral integration.Keywords
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