Effect of Theophylline as Adjunct to Inhaled Corticosteroids on Exacerbations in Patients With COPD
Open Access
- 16 October 2018
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 320 (15) , 1548-1559
Abstract
Chronic obstructive pulmonary disease (COPD) is well recognized as a major growing global health concern.1,2 An important clinical feature of COPD is acute exacerbations, which are adversely associated with morbidity3 and mortality4 and are the most costly aspect of COPD for health care systems.2Keywords
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