Hepatic Fibrinogen Deposits in Pre-Eclampsia
Authors:
- 9 September 1976
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 295 (11) , 578-582
Abstract
To investigate if fibrin (or fibrinogen), immunoglobulins and complement were present in the liver of patients with toxemia of pregnancy, we performed immunofluorescence studies on needle biopsies of pre-eclamptic women. Fibrin (or fibrinogen) outlining the hepatic sinusoids was found in all 12 cases; in two of them there were also large nodular deposits of fibrin (or fibrinogen) and to a lesser extent of IgG, IgM and C3 in areas of necrosis. Immunofluorescence study of 13 control liver biopsies, six from pregnant women, was negative.Keywords
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