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Figure S7 from Chronic ISG15 Exposure Accelerates CD8+ T-cell Dysfunction while Increasing PD-1 Blockade Sensitivity in Oral Squamous Cell Carcinoma
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Figure S7 from Chronic ISG15 Exposure Accelerates CD8+ T-cell Dysfunction while Increasing PD-1 Blockade Sensitivity in Oral Squamous Cell Carcinoma
Figure S7 from Chronic ISG15 Exposure Accelerates CD8+ T-cell Dysfunction while Increasing PD-1 Blockade Sensitivity in Oral Squamous Cell Carcinoma
Authors:
YC
Yu-Lin Chen
Yu-Lin Chen
AY
Amir Yousif
Amir Yousif
CC
Chung-Hsing Chen
Chung-Hsing Chen
AL
Ava Lowin
Ava Lowin
AS
Abbey A. Saadey
Abbey A. Saadey
SW
Ssu-Han Wang
Ssu-Han Wang
SJ
Shih Sheng Jiang
Shih Sheng Jiang
YC
Ya-Wen Chen
Ya-Wen Chen
HG
Hazem E. Ghoneim
Hazem E. Ghoneim
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3 November 2025
other
Published by
American Association for Cancer Research (AACR)
DOI:
10.1158/2326-6066.30516144
Abstract
Suppl. Fig S7: High Isg15 tumor expression was associated with reduced CD8+ T cell activity.
Keywords
HEAD, NECK & ORAL CANCERS
IMMUNOLOGY
T CELL EXHAUSTION
IMMUNOTHERAPY
CHECKPOINT BLOCKADE
TUMOR MICROENVIRONMENT
INFLAMATION AND THE MICROENVIRONMENT
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