Axial, sagittal and coronal gadolinium-enhanced MRI at pre-baseline (A-C; yellow arrows), 6 months later demonstrating complete response after anlotinib plus temozolomide (E-G). Axial Fluid-Attenuated Inversion Recovery (FLAIR, D) image at pre-baseline, and no progression was observed during anlotinib plus temozolomide treatment after 6 months (H).