Human Y-Chromosome-Specific Reiterated DNA

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Abstract
Radiolabeled reiterated DNA specific for the human Y chromosome has been obtained by extensive reassociations between [ 3 H]DNA prepared from men and excess DNA from women. These highly purified labeled sequences reassociate only with DNA from individuals with a Y chromosome. The percentage of Y-chromosome-specific DNA isolated from individuals with differing numbers of Y chromosomes is a function of the number of Y chromosomes present. The purified Y-chromosome-specific sequences may represent between 7 and 11 percent of the human Y chromosome.