Inhibition of c-Src Tyrosine Kinase Prevents Angiotensin II–Mediated Connexin-43 Remodeling and Sudden Cardiac Death
- 1 November 2011
- Vol. 58 (22) , 2332-2339
Abstract
No abstract availableKeywords
Funding Information
- National Institutes of Health (RO1 RO1HL085558, P01 HL058000)
- American Heart Association Midwest Affiliate Postdoctoral Fellowship (AHA10POST4450037)
This publication has 29 references indexed in Scilit:
- 2-Aminothiazole as a Novel Kinase Inhibitor Template. Structure−Activity Relationship Studies toward the Discovery of N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1- piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5-carboxamide (Dasatinib, BMS-354825) as a Potent pan-Src Kinase InhibitorJournal of Medicinal Chemistry, 2006
- N-(5-Chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5- (tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine, a Novel, Highly Selective, Orally Available, Dual-Specific c-Src/Abl Kinase InhibitorJournal of Medicinal Chemistry, 2006
- Inhibition of Src Expression and Activity Inhibits Tumor Progression and Metastasis of Human Pancreatic Adenocarcinoma Cells in an Orthotopic Nude Mouse ModelThe American Journal of Pathology, 2006
- A novel activating function of c-Src and Stat3 on HGF transcription in mammary carcinoma cellsOncogene, 2006
- Mechanisms of sudden cardiac deathJournal of Clinical Investigation, 2005
- Rethinking the Renin-Angiotensin System and Its Role in Cardiovascular RegulationCardiovascular Drugs and Therapy, 2005
- Structural basis for selective inhibition of Src family kinases by PP1Chemistry & Biology, 1999
- Independent prognostic information provided by sphygmomanometrically determined pulse pressure and mean arterial pressure in patients with left ventricular dysfunctionJACC, 1999
- Src family‐selective tyrosine kinase inhibitor, PP1, inhibits both FcεRI‐ and Thy‐1‐mediated activation of rat basophilic leukemia cellsEuropean Journal of Immunology, 1997
- Effects of cilazapril on ventricular arrhythmia in patients with congestive heart failureClinical Therapeutics, 1997