Prolonged gene silencing by siRNA/chitosan-g-deoxycholic acid polyplexes loaded within biodegradable polymer nanoparticles
Authors:
- Soo Hyeon LeeSLSoo Hyeon Lee
- Mi Hwa OhMOMi Hwa Oh
- Jee Seon KimJKJee Seon Kim
- Tae Gwan ParkTPTae Gwan Park
- Yoon Sung NamYNYoon Sung Nam
- 1 September 2012
- journal article
- Published by Elsevier in Journal of Controlled Release
- Vol. 162 (2) , 407-413
Abstract
No abstract availableKeywords
Funding Information
- Ministry of Health, Welfare and Family Affairs, Republic of Korea (A040041, A111552)
This publication has 38 references indexed in Scilit:
- Self-assembled siRNA–PLGA conjugate micelles for gene silencingJournal of Controlled Release, 2011
- Multimeric small interfering ribonucleic acid for highly efficient sequence-specific gene silencingNature Materials, 2010
- siRNA Conjugate Delivery SystemsBioconjugate Chemistry, 2008
- Local and systemic delivery of VEGF siRNA using polyelectrolyte complex micelles for effective treatment of cancerJournal of Controlled Release, 2008
- RNA-based therapiesNature Reviews Drug Discovery, 2007
- The influence of polymeric properties on chitosan/siRNA nanoparticle formulation and gene silencingBiomaterials, 2007
- RNAi therapeutics: a potential new class of pharmaceutical drugsNature Chemical Biology, 2006
- The RNAi revolutionNature, 2004
- siRNAs: applications in functional genomics and potential as therapeuticsNature Reviews Drug Discovery, 2004
- Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegansNature, 1998