Higher G2 sensitivity to the induction of chromosomal damage in the CHO mutant EM9 than in its parental line AA8 by camptothecin, an inhibitor of DNA topoisomerase I
Authors:
- 1 February 1993
- journal article
- Published by Elsevier in Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
- Vol. 285 (2) , 281-285
Abstract
No abstract availableKeywords
This publication has 10 references indexed in Scilit:
- Camptothecin cytotoxicity in mammalian cells is associated with the induction of persistent double strand breaks in replicating DNANucleic Acids Research, 1991
- Relationship between the Recovery from Sublethal X-Ray Damage and the Rejoining of Chromosome Breaks in Normal Human FibroblastsRadiation Research, 1987
- A Quantitative Comparison of Potentially Lethal Damage Repair and the Rejoining of Interphase Chromosome Breaks in Low Passage Normal Human FibroblastsRadiation Research, 1987
- Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I.Journal of Biological Chemistry, 1985
- Bloom's syndrome and EM9 cells in BrdU-containing medium exhibit similarly elevated frequencies of sister chromatid exchange but dissimilar amounts of cellular proliferation and chromosome disruptionChromosoma, 1984
- DNA-ligase activities appear in the CHO mutant EM9Mutation Research/DNA Repair Reports, 1984
- The relationship between sister-chromatid exchange and perturbations in DNA replication in mutant EM9 and normal CHO cellsMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1983
- A CHO-cell strain having hypersensitivity to mutagens, a defect in DNA strand-break repair, and an extraordinary baseline frequency of sister-chromatid exchangeMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1982
- Contribution of incorporated 5-bromodeoxyuridine in DNA to the frequencies of sister-chromatid exchanges induced by inhibitors of poly-(ADP-ribose)-polymeraseMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1981
- Molecular mechanisms involved in the production of chromosomal aberrationsMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1978