Supplementary Figure 6 from PARP7 Inhibitors and AHR Agonists Act Synergistically across a Wide Range of Cancer Models

Authors:

HCHuadong Chen
Huadong Chen
XGXuxu Gou
Xuxu Gou
YMYing Mao
Ying Mao
POPatrick C. O’LEary
Patrick C. O’LEary
MDMorgan E. Diolaiti
Morgan E. Diolaiti
AAAlan Ashworth
Alan Ashworth

Open Access

Publisher website

Google Scholar

17 June 2026

other
Published by American Association for Cancer Research (AACR)

DOI:10.1158/1535-7163.32712729

Abstract

Supplementary Fig. 6 PARP7i and AHRa synergistically suppress the in vitro growth of hormone-resistant cancer cell lines and promote proteasomal turnover of hormone receptors

Keywords

DRUG MECHANISMS
CELLULAR RESPONSES TO ANTICANCER DRUGS
ENDOCRINE-RELATED CANCERS
ENDOCRINOLOGY
STEROID HORMONES AND RECEPTORS
SMALL MOLECULE AGENTS