Exendin-4 gene modification and microscaffold encapsulation promote self-persistence and antidiabetic activity of MSCs
Open Access
- 2 July 2021
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science Advances
- Vol. 7 (27) , eabi4379
Abstract
This study revealed the enhanced therapeutic effects and mechanisms of Exendin-4–engineered MSCs for type 2 diabetes treatment.Keywords
Funding Information
- National Natural Science Foundation of China (82061148010)
- China Postdoctoral Science Foundation (2019M650717)
- Beijing Municipal Science and Technology Commission, Adminitrative Commission of Zhongguancun Science Park (Z181100001818005)
- National Key Research and Development Program of China Stem Cell and Translational Research (2017YFA0104901)
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