Cyclic AMP-dependent synthesis of fimbriae in Salmonella typhimurium: effects of cya and pts mutations

Authors:
  • MSM H Saier
    M H Saier
  • MSM R Schmidt
    M R Schmidt
  • MLM Leibowitz
    M Leibowitz

Abstract
Synthesis of bacterial fimbriae (group 1, subtype 1) was dependent on cyclic AMP and was subject to catabolite repression by many carbohydrates. Mutations in the genes coding for the energy-coupling protein constituents of the phosphoenolpyruvate:sugar phosphotransferase system prevented repression of fimbrial production by the sugar substrates of this enzyme system.