Comparison of a Target Trial Emulation Framework vs Cox Regression to Estimate the Association of Corticosteroids With COVID-19 Mortality

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Abstract
Observational databases are invaluable resources when randomized clinical trials (RCTs) are infeasible or unavailable. However, the correctness of the conclusions gleaned from analyses of observational data hinges on the careful consideration of study design principles and choice of estimation methods.1-4
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