Antibiotic tolerance in strains of Staphylococcus aureus
Authors:
- 1 June 1981
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Antimicrobial Chemotherapy
- Vol. 7 (6) , 599-605
Abstract
The frequency of tolerance in 13 strains of Staphylococcus aureus was examined .using two media (MHB and BHI broth) and two methods (broth dilution and time-kill curves). In broth dilution tests, tolerance was found more frequently in MHB than BHI; a similar, but much smaller effect was noted in time-kill curves. There were also discrepancies (with both BHI and MHB) between the two methods of testing as to whether a strain was called tolerant. The significance of these technical variations will probably require correlation with clinical studies to determine the most useful methods of testing for tolerance.Keywords
This publication has 7 references indexed in Scilit:
- Serious staphylococcal infections with strains tolerant to bactericidal antibioticsArchives of internal medicine (1960), 1979
- Significance of Methicillin Tolerance in Experimental Staphylococcal EndocarditisAntimicrobial Agents and Chemotherapy, 1979
- Antibiotic-tolerant Staphylococcus aureusJournal of Antimicrobial Chemotherapy, 1978
- Staphylococcus aureus endocarditis. Combined therapy with vancomycin and rifampinJAMA, 1978
- Incidence and Characteristics of Antibiotic-Tolerant Strains of Staphylococcus aureusAntimicrobial Agents and Chemotherapy, 1978
- Medium-Dependent Variation in Bactericidal Activity of Antibiotics Against Susceptible Staphylococcus aureusAntimicrobial Agents and Chemotherapy, 1978
- A NEW TYPE OF PENICILLIN RESISTANCE OF STAPHYLOCOCCUS AUREUSThe Lancet, 1977