Ostrich (Struthio camelus) Infected with H5N8 Highly Pathogenic Avian Influenza Virus in South Korea in 2014
Authors:
- Il- JangIJIl- Jang
- You-Chan BaeYBYou-Chan Bae
- 1 June 2016
- journal article
- research article
- Published by American Association of Avian Pathologists (AAAP) in Avian Diseases
- Vol. 60 (2) , 535-539
Abstract
SUMMARY Highly pathogenic avian influenza (HPAI) virus of the H5N8 subtype was isolated from a young ostrich in South Korea in March 2014. Clinical signs characterized by anorexia, depression, and signs of nervousness were observed. The isolated A/ostrich/Korea/H829/2014 (H5N8) virus had a cleavage site motif containing multiple basic amino acids, typical of HPAI virus. The phylogenetic tree of the hemagglutinin gene of the H5 HPAI virus showed that this ostrich H5N8 virus belongs to clade 2.3.4.4 viruses together with H5N8 strains isolated from ducks and wild birds in South Korea in 2014. Pathologically, redness of pancreas, enlargement and hemorrhage of spleen, friability of brain, and hydropericardium were prominently found. Histologic legions were observed in pancreas, spleen, liver, lung, heart, and brain, and influenza A nucleoproteins were detected in the same organs by immunohistochemistry. Other ostriches farmed together in open camps were not infected with HPAI virus based on the serologic and v... RESUMEN Reporte de caso- Avestruz (Struthio camelus) infectada con el virus de la influenza aviar altamente patógena subtipo H5N8 en Corea del Sur en el año 2014. El virus de la influenza aviar altamente patógena (con las siglas en inglés HPAI), subtipo H5N8 se aisló de una avestruz joven en Corea del Sur en marzo del año 2014. Se observaron signos clínicos caracterizados por anorexia, depresión, y nerviosismo. El aislamiento A/avestruz/Corea/H829/2014 (H5N8) mostró un motivo en el sitio de disociación que contenía múltiples aminoácidos básicos, típicos del virus de la influenza aviar altamente patógena. El árbol filogenético con genes de la hemaglutinina de virus H5 de influenza aviar altamente patógenos mostró que este virus H5N8 de avestruz pertenecía al clado 2.3.4.4 junto con cepas del subtipo H5N8 aisladas de patos y aves silvestres en Corea del Sur en el año 2014. Desde el punto de vista patológico, se observaron predominantemente enrojecimiento de páncreas, agrandamiento y hemorragias del bazo, fr...Keywords
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