Alobar holoprosencephaly at 9 weeks gestational age visualized by two‐ and three‐dimensional ultrasound

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Abstract
We present the ultrasound detection of alobar holoprosencephaly (HPE) with cyclopia in an embryo of 9 weeks 2 days last menstrual period (LMP)‐based gestational age; the crown–rump length (CRL) was 22 mm. The use of three‐dimensional (3‐D) ultrasound made additional diagnostic ultrasound tomograms possible, and the volume reconstructions improved the imaging and the understanding of the condition.

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