An integrative pharmacogenomics analysis identifies therapeutic targets in KRAS-mutant lung cancer
Open Access
- 1 November 2019
- journal article
- research article
- Published by Elsevier in EBioMedicine
- Vol. 49, 106-117
Abstract
No abstract availableKeywords
This publication has 61 references indexed in Scilit:
- Systematic identification of genomic markers of drug sensitivity in cancer cellsNature, 2012
- The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivityNature, 2012
- Hallmarks of Cancer: The Next GenerationCell, 2011
- COT drives resistance to RAF inhibition through MAP kinase pathway reactivationNature, 2010
- RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAFNature, 2010
- Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1Nature, 2009
- A Gene Expression Signature Associated with “K-Ras Addiction” Reveals Regulators of EMT and Tumor Cell SurvivalCancer Cell, 2009
- Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profilesProceedings of the National Academy of Sciences, 2005
- Protein kinase CK2 phosphorylates and upregulates Akt/PKBCell Death & Differentiation, 2005
- Dissemination and growth of cancer cells in metastatic sitesNature Reviews Cancer, 2002