Characterization of the Horizontal and Vertical Sexual Transmission ofChlamydiaGenital Infections in a New Mouse Model
Authors:
- 1 July 2019
- journal article
- research article
- Published by American Society for Microbiology in Infection and Immunity
- Vol. 87 (7)
Abstract
Chlamydia trachomatisis the most common sexually transmitted bacterial pathogen worldwide, and there is a need to control this epidemic. So far there is no established animal model in which both the horizontal and the vertical transmission ofChlamydiacan be studied. To implement a horizontal sexual transmission model, male mice were inoculated in the meatus urethra withChlamydia muridarumand they were caged with naive female mice. Urine and vaginal swab specimens were collected for culture.Keywords
Funding Information
- HHS | NIH | National Institute of Allergy and Infectious Diseases (AI204286)
- HHS | NIH | National Institute of Allergy and Infectious Diseases (AI092129)
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