Clathrin light chains contain brain-specific insertion sequences and a region of homology with intermediate filaments
Authors:
- Antony P. JacksonAntony P. Jackson
- Heng-Fong SeowHSHeng-Fong Seow
- Nicholas HolmesNHNicholas Holmes
- Kurt DrickamerKDKurt Drickamer
- Peter ParhamPPPeter Parham
- 1 March 1987
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 326 (6109) , 154-159
Abstract
The primary structures of four bovine clathrin light chains have been determined. Light chains LCa and LCb are homologous proteins encoded by different genes. In the brain the messenger RNA from these genes undergoes differential splicing to yield proteins having centrally inserted brain-specific sequences. A potentially alpha-helical region of the clathrin light chains shows homology with intermediate filament proteins.Keywords
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