Regulation of entry into gametogenesis
Open Access
- 27 December 2011
- journal article
- review article
- Published by The Royal Society in Philosophical Transactions of the Royal Society B: Biological Sciences
- Vol. 366 (1584) , 3521-3531
Abstract
Gametogenesis is a fundamental aspect of sexual reproduction in eukaryotes. In the unicellular fungi Saccharomyces cerevisiae (budding yeast) and Schizosaccharomyces pombe (fission yeast), where this developmental programme has been extensively studied, entry into gametogenesis requires the convergence of multiple signals on the promoter of a master regulator. Starvation signals and cellular mating-type information promote the transcription of cell fate inducers, which in turn initiate a transcriptional cascade that propels a unique type of cell division, meiosis, and gamete morphogenesis. Here, we will provide an overview of how entry into gametogenesis is initiated in budding and fission yeast and discuss potential conserved features in the germ cell development of higher eukaryotes.Keywords
This publication has 99 references indexed in Scilit:
- Licensing of gametogenesis, dependent on RNA binding protein DAZL, as a gateway to sexual differentiation of fetal germ cellsProceedings of the National Academy of Sciences, 2011
- Plzf Regulates Germline Progenitor Self-Renewal by Opposing mTORC1Cell, 2010
- Distinct Phosphatase Requirements and GATA Factor Responses to Nitrogen Catabolite Repression and Rapamycin Treatment in Saccharomyces cerevisiaeJournal of Biological Chemistry, 2010
- Importance of polyadenylation in the selective elimination of meiotic mRNAs in growing S. pombe cellsThe EMBO Journal, 2010
- Initiation of the TORC1-Regulated G0 Program Requires Igo1/2, which License Specific mRNAs to Evade Degradation via the 5′-3′ mRNA Decay PathwayMolecular Cell, 2010
- STRA8 Shuttles between Nucleus and Cytoplasm and Displays Transcriptional ActivityJournal of Biological Chemistry, 2009
- Stra8 and its inducer, retinoic acid, regulate meiotic initiation in both spermatogenesis and oogenesis in miceProceedings of the National Academy of Sciences, 2008
- Control of Meiosis by RespirationCurrent Biology, 2008
- Meiosis-Specific Destruction of the Ume6p Repressor by the Cdc20-Directed APC/CMolecular Cell, 2007
- In germ cells of mouse embryonic ovaries, the decision to enter meiosis precedes premeiotic DNA replicationNature Genetics, 2006