Solubilization and Wetting Effects of Bile Salts on the Dissolution of Steroids
Authors:
- 1 December 1991
- journal article
- research article
- Published by Springer Nature in Pharmaceutical Research
- Vol. 8 (12) , 1461-1469
Abstract
The ability of sodium taurocholate to increase the initial dissolution rate of five steroids was studied in terms of effects on solubility, wetting, and diffusion coefficient. For all compounds,...Keywords
This publication has 36 references indexed in Scilit:
- Physicochemical Basis of Increased Bioavailability of a Poorly Water-Soluble Drug following Oral Administration as Organic SolutionsJournal of Pharmaceutical Sciences, 1988
- Cholesterol Monohydrate Dissolution Rate Studies in Aqueous Micellar Sodium Chenodeoxycholate SolutionsJournal of Pharmaceutical Sciences, 1985
- Interaction of drugs with bile components. I. Effects of bile salts on the dissolution behavior of indomethacin and phenylbutazone.Chemical and Pharmaceutical Bulletin, 1979
- Wettability of Pharmaceutical Solids: Estimates of Solid Surface PolarityJournal of Pharmaceutical Sciences, 1976
- Micelle Formation and Testosterone Solubilization by Sodium GlycocholateJournal of Pharmaceutical Sciences, 1972
- Physiologic Surface-Active Agents and Drug Absorption IV: Effect of Pre-Micellar Concentrations of Surfactant on Dissolution RateJournal of Pharmaceutical Sciences, 1969
- Dissolution Kinetics of Drugs in Human Gastric Juice—The Role of Surface TensionJournal of Pharmaceutical Sciences, 1968
- Establishment of sink conditions in dissolution rate determinations. Theoretical considerations and application to nondisintegrating dosage formsJournal of Pharmaceutical Sciences, 1967
- Solubilizing Properties of Bile Salt Solutions II.Journal of Pharmaceutical Sciences, 1966
- On the Concentration of Bile Acids in the Human Intestine during Absorption. Bile Acids and Steroids 74.Acta Physiologica Scandinavica, 1959