Vascular Smooth Muscle: Aerobic Glycolysis Linked to Sodium and Potassium Transport Processes
Authors:
- 21 December 1979
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 206 (4425) , 1414-1416
Abstract
Under aerobic conditions, glucose is primarily catabolized by vascular smooth muscle to lactate, in spite of an adequate oxidative capacity. Although this is often considered to be indicative of some nonspecific metabolic insufficiency, there is evidence that aerobic glycolysis is specifically coupled to sodium and potassium transport processes, whereas oxidative metabolism is coupled to contractile energy requirements.Keywords
This publication has 15 references indexed in Scilit:
- Mechanical, Electrical, and Biochemical Effects of Hypoxia and Substrate Removal on Spontaneously Active Vascular Smooth MuscleActa Physiologica Scandinavica, 1977
- Morphology and metabolism of an aortic intima-media preparation in which an intact endothelium is preserved.Journal of Clinical Investigation, 1976
- Aerobic glycolysis in vascular smooth muscle: Relation to isometric tensionBiochimica et Biophysica Acta (BBA) - Bioenergetics, 1974
- Oxygen sensitivity of vascular smooth muscleMicrovascular Research, 1973
- Effects of Increasing Glucose Concentrations on the Glucose Metabolism in Arterial Tissue and Intestinal Smooth MuscleActa Physiologica Scandinavica, 1973
- Potassium accumulation in smooth muscle and associated ultrastructural changesThe Journal of Physiology, 1973
- Biochemical Alterations Caused by Hypoxia in the Isolated Rabbit Aorta: CORRELATION WITH CHANGES IN ARTERIAL CONTRACTILITYCirculation Research, 1973
- The relationship between the transport of glucose and cations across cell membranes in isolated tissuesBiochimica et Biophysica Acta (BBA) - Biomembranes, 1972
- Sodium–Potassium Stimulated Adenosinetriphosphatase of Vascular Smooth MuscleCanadian Journal of Biochemistry, 1971
- The relationship between the transport of glucose and cations across cell membranes in isolated tissues III. Effect of Na+ and hyperosmolarity on glucose metabolism and insulin responsiveness in isolated rat hemidiaphragmBiochimica et Biophysica Acta (BBA) - Biomembranes, 1968