In vitro and in vivo antitumor activity of the NF-κB inhibitor DHMEQ in the human T-cell leukemia virus type I-infected cell line, HUT-102
Authors:
- Takeo OhsugiTakeo Ohsugi
- Toshio KumasakaTKToshio Kumasaka
- Akira IshidaAIAkira Ishida
- Takaomi IshidaTITakaomi Ishida
- Ryouichi HorieRHRyouichi Horie
- Toshiki WatanabeTWToshiki Watanabe
- Kazuo UmezawaKUKazuo Umezawa
- Kazunari YamaguchiKYKazunari Yamaguchi
- 1 January 2006
- journal article
- Published by Elsevier in Leukemia Research
- Vol. 30 (1) , 90-97
Abstract
No abstract availableKeywords
This publication has 19 references indexed in Scilit:
- A novel NF-?B inhibitor DHMEQ selectively targets constitutive NF-?B activity and induces apoptosis of multiple myeloma cellsin vitro andin vivoInternational Journal of Cancer, 2004
- Tax-Independent Constitutive IκB Kinase Activation in Adult T-Cell Leukemia CellsNeoplasia, 2004
- Inhibition of Tumor Necrosis Factor-α-induced Nuclear Translocation and Activation of NF-κB by DehydroxymethylepoxyquinomicinJournal of Biological Chemistry, 2002
- Bay 11-7082 inhibits transcription factor NF-kappa B and induces apoptosis of HTLV-I-infected T-cell lines and primary adult T-cell leukemia cellsBlood, 2002
- Synthesis of NF-κB activation inhibitors derived from epoxyquinomicin CBioorganic & Medicinal Chemistry Letters, 2000
- Persistent activation of NF-κB by the Tax transforming protein of HTLV-1: hijacking cellular IκB kinasesOncogene, 1999
- Complementation Cloning of NEMO, a Component of the IκB Kinase Complex Essential for NF-κB ActivationCell, 1998
- Epoxyquinomicins A, B, C and D, New Antibiotics from Amycolatopsis. II. Effect on Type II Collagen-induced Arthritis in Mice.The Journal of Antibiotics, 1997
- Adult T-cell leukemia: antigen in an ATL cell line and detection of antibodies to the antigen in human sera.Proceedings of the National Academy of Sciences, 1981
- Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphomaProceedings of the National Academy of Sciences, 1980