LRIG inhibitors of growth factor signalling – double-edged swords in human cancer?
Authors:
- Håkan HedmanHHHåkan Hedman
- Roger HenrikssonRHRoger Henriksson
- 1 March 2007
- journal article
- review article
- Published by Elsevier in European Journal of Cancer
- Vol. 43 (4) , 676-682
Abstract
No abstract availableKeywords
This publication has 43 references indexed in Scilit:
- A soluble ectodomain of LRIG1 inhibits cancer cell growth by attenuating basal and ligand-dependent EGFR activityOncogene, 2006
- LRIG-1 Provides a Novel Prognostic Predictor in Squamous Cell Carcinoma of the Skin: Immunohistochemical Analysis for 38 CasesDermatologic Surgery, 2006
- The Leucine-rich Repeat Protein LRIG1 Is a Negative Regulator of ErbB Family Receptor Tyrosine KinasesJournal of Biological Chemistry, 2004
- LRIG1 restricts growth factor signaling by enhancing receptor ubiquitylation and degradationThe EMBO Journal, 2004
- The LRIG gene family has three vertebrate paralogs widely expressed in human and mouse tissues and a homolog in AscidiaceaGenomics, 2004
- Characterization and tissue-specific expression of human LRIG2Gene, 2004
- LRIG1 and epidermal growth factor receptor in renal cell carcinoma: a quantitative RT–PCR and immunohistochemical analysisBritish Journal of Cancer, 2003
- Is LRIG1 a Tumour Suppressor Gene at Chromosome 3p14.3?Acta Oncologica, 2002
- Cloning, Characterization, and Expression of Human LIG1Biochemical and Biophysical Research Communications, 2001
- cDNA Cloning of a Novel Membrane Glycoprotein That Is Expressed Specifically in Glial Cells in the Mouse BrainJournal of Biological Chemistry, 1996