Distribution of Antiseptic Resistance Genes qacA, qacB , and smr in Methicillin-Resistant Staphylococcus aureus Isolated in Toronto, Canada, from 2005 to 2009
- 1 June 2011
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 55 (6) , 2999-3001
Abstract
Decreased susceptibility to chlorhexidine gluconate (CHDN) in methicillin-resistant Staphylococcus aureus (MRSA) is associated with the qacA , qacB , and smr genes, encoding efflux pumps. A total of 334 MRSA isolates were collected from two Canadian intensive care units between 2005 and 2009. We identified the qacAB genes in 7 strains (2%; 2 qacA genes and 5 qacB genes) and the smr gene in 23 (7%) strains. CHDN minimal bactericidal concentrations were slightly higher for strains harboring smr genes.Keywords
This publication has 20 references indexed in Scilit:
- Genome Sequence of a Recently Emerged, Highly Transmissible, Multi-Antibiotic- and Antiseptic-Resistant Variant of Methicillin-Resistant Staphylococcus aureus , Sequence Type 239 (TW)Journal of Bacteriology, 2010
- Efficacy and Limitation of a Chlorhexidine‐Based Decolonization Strategy in Preventing Transmission of Methicillin‐ResistantStaphylococcus aureusin an Intensive Care UnitClinical Infectious Diseases, 2010
- Epidemiology and susceptibilities of methicillin-resistant Staphylococcus aureus in Taiwan: emphasis on chlorhexidine susceptibilityDiagnostic Microbiology and Infectious Disease, 2009
- Frequency of biocide resistance genes, antibiotic resistance and the effect of chlorhexidine exposure on clinical methicillin-resistant Staphylococcus aureus isolatesJournal of Antimicrobial Chemotherapy, 2008
- Antimicrobial Agent of Susceptibilities and Antiseptic Resistance Gene Distribution among Methicillin-Resistant Staphylococcus aureus Isolates from Patients with Impetigo and Staphylococcal Scalded Skin SyndromeJournal of Clinical Microbiology, 2006
- Typing of Methicillin-Resistant Staphylococcus aureus in a University Hospital Setting by Using Novel Software for spa Repeat Determination and Database ManagementJournal of Clinical Microbiology, 2003
- Rapid Detection of Methicillin-Resistant Staphylococci from Blood Culture Bottles by Using a Multiplex PCR AssayJournal of Clinical Microbiology, 2002
- Antiseptic susceptibility and distribution of antiseptic-resistance genes in methicillin-resistantStaphylococcus aureusFEMS Microbiology Letters, 1999
- Substrate specificity and energetics of antiseptic and disinfectant resistance in Staphylococcus aureusFEMS Microbiology Letters, 1992
- Substrate specificity and energetics of antiseptic and disinfectant resistance inStaphylococcus aureusFEMS Microbiology Letters, 1992