Frontal Lobe Metabolic Decreases with Sleep Deprivation not Totally Reversed by Recovery Sleep
- 26 July 2006
- journal article
- research article
- Published by Springer Nature in Neuropsychopharmacology
- Vol. 31 (12) , 2783-2792
Abstract
We studied the effects of total sleep deprivation and recovery sleep in normal subjects using position emission tomography with 18F-deoxyglycose. Sleep deprivation resulted in a significant decrease in relative metabolism of the frontal cortex, thalamus, and striatum. Recovery sleep was found to have only a partial restorative effect on frontal lobe function with minimal reversal of subcortical deficits. Sleep may be especially important for maintenance of frontal lobe activity.Keywords
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