‘Big bang’ of B-cell development revealed
Open Access
- 15 January 2018
- journal article
- editorial
- Published by Cold Spring Harbor Laboratory in Genes & Development
- Vol. 32 (2) , 93-95
Abstract
Earlier studies have identified transcription factors that specify B-cell fate, but the underlying mechanisms remain to be revealed. Two new studies by Miyai and colleagues (pp. 112–126) and Li and colleagues (pp. 96–111) in this issue of Genes & Development provide new and unprecedented insights into the genetic and epigenetic mechanisms that establish B-cell identity.Keywords
Funding Information
- National Institutes of Health (1P01AI102853-01, 1RO1 AI109599-27)
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