DT-Web: a web-based application for drug-target interaction and drug combination prediction through domain-tuned network-based inference
Open Access
- 1 June 2015
- journal article
- Published by Springer Nature in BMC Systems Biology
- Vol. 9 (S3) , S4
Abstract
The identification of drug-target interactions (DTI) is a costly and time-consuming step in drug discovery and design. Computational methods capable of predicting reliable DTI play an important role in the field. Algorithms may aim to design new therapies based on a single approved drug or a combination of them. Recently, recommendation methods relying on network-based inference in connection with knowledge coming from the specific domain have been proposed.Keywords
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