Destruction of a Destructor: A New Avenue for Cancer Therapeutics Targeting the Wnt Pathway
Authors:
Open Access
- 11 December 2009
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Molecular Cell Biology
- Vol. 2 (2) , 70-73
Abstract
A new study in Nature has identified a small molecule inhibitor for the oncogenic Wnt/β-catenin pathway that is responsible for many human cancers. This inhibitor targets an unsuspected cellular enzyme, Tankyrase, which controls the destruction of a β-catenin destructor.Keywords
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