Encapsulation of Carotenoids as Food Colorants via Formation of Cyclodextrin Inclusion Complexes: A Review
Open Access
- 5 June 2021
- journal article
- review article
- Published by MDPI AG in Polysaccharides
- Vol. 2 (2) , 454-476
Abstract
The use of natural carotenoids as food colorants is an important trend of innovation in the industry due to their low toxicity, their potential as bio-functional ingredients, and the increasing demand for natural and organic foods. Despite these benefits, their inclusion in food matrices presents multiple challenges related to their low stability and low water solubility. The present review covers the main concepts and background of carotenoid inclusion complex formation in cyclodextrins as a strategy for their stabilization, and subsequent inclusion in food products as color additives. The review includes the key aspects of the molecular and physicochemical properties of cyclodextrins as complexing agents, and a detailed review of the published evidence on complex formation with natural carotenoids from different sources in cyclodextrins, comparing complex formation methodologies, recovery, inclusion efficiency, and instrumental characterization techniques. Moreover, process flow diagrams (PFD), based on the most promising carotenoid-cyclodextrin complex formation methodologies reported in literature, are proposed, and discussed as a potential tool for their future scale-up. This review shows that the inclusion of carotenoids in complexes with cyclodextrins constitutes a promising technology for the stabilization of these pigments, with possible advantages in terms of their stability in food matrices.Keywords
All Related Versions
Funding Information
- Departamento Administrativo de Ciencia, Tecnología e Innovación (COLCIENCIAS) (448422712018)
This publication has 59 references indexed in Scilit:
- Preparation of lutein proliposomes by supercritical anti-solvent techniqueFood Hydrocolloids, 2012
- Carotenoids and β-Cyclodextrin Inclusion Complexes: Raman Spectroscopy and Theoretical InvestigationThe Journal of Physical Chemistry A, 2011
- Effect of different antioxidants on lycopene degradation in oil‐in‐water emulsionsEuropean Journal of Lipid Science and Technology, 2011
- Carotenoids in Food2009
- Preparation and Solid-State Characterization of Inclusion Complexes Formed Between Miconazole and Methyl-β-CyclodextrinAAPS PharmSciTech, 2008
- Nanoencapsulation I. Methods for preparation of drug-loaded polymeric nanoparticlesNanomedicine: Nanotechnology, Biology and Medicine, 2006
- Inclusion complexes of carotenoids with cyclodextrins: 1HNMR, EPR, and optical studiesFree Radical Biology and Medicine, 2004
- Study of β-blockers/β-cyclodextrins inclusion complex by NMR, DSC, X-ray and SEM investigationJournal of Pharmaceutical and Biomedical Analysis, 2000
- Natural Pigments: Carotenoids, Anthocyanins, and Betalains — Characteristics, Biosynthesis, Processing, and StabilityCritical Reviews in Food Science and Nutrition, 2000
- Resonance Raman spectroscopy of carotenoids and carotenoid-containing systemsPure and Applied Chemistry, 1985