CD4 + T cell activation and concomitant mTOR metabolic inhibition can ablate microbiota-specific memory cells and prevent colitis
- 18 December 2020
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science Immunology
- Vol. 5 (54)
Abstract
Activation by multi-epitope peptide plus mTOR inhibition depletes flagellin-reactive CD4 + T cells and prevents intestinal inflammation.Keywords
Funding Information
- National Institutes of Health (P01 DK071176)
- National Institutes of Health (P30 AI27667)
- National Institutes of Health (P30 AR048311)
- National Institutes of Health (RR-20136)
- National Institutes of Health (DK118386)
- Crohn’s and Colitis Foundation
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