Relation between Mutations of the Cystic Fibrosis Gene and Idiopathic Pancreatitis
Authors:
- Kenneth J. FriedmanKFKenneth J. Friedman
- Peadar G. NoonePNPeadar G. Noone
- Michael R. KnowlesMKMichael R. Knowles
- Lawrence M. SilvermanLSLawrence M. Silverman
- Paul S. JowellPJPaul S. Jowell
Open Access
- 3 September 1998
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 339 (10) , 653-658
Abstract
It is unknown whether genetic factors predispose patients to idiopathic pancreatitis. In patients with cystic fibrosis, mutations of the cystic fibrosis transmembrane conductance regulator (CFTR ) gene typically cause pulmonary and pancreatic insufficiency while rarely causing pancreatitis. We examined whether idiopathic pancreatitis is associated with CFTR mutations in persons who do not have lung disease of cystic fibrosis.Keywords
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