Designs for Experiments — Parallel Comparisons of Treatment

Authors:
  • PLPhilip W. Lavori
    Philip W. Lavori
  • TLThomas A. Louis
    Thomas A. Louis
  • JBJohn C. Bailar
    John C. Bailar
  • MPMarcia Polansky
    Marcia Polansky
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Abstract
Clinical trials of medical treatments often compare two treated groups or a treated group with a separate but concurrent control group. We have examined a consecutive series of 47 such parallel studies reported in the Journal in 1978–1979, including 35 with random assignment to the treated or control group, to discover how this approach is actually used.

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