Target Blood Pressure for Treatment of Isolated Systolic Hypertension in the Elderly

Authors:
  • TSTakao Saruta
    Takao Saruta
  • HMHiroaki Matsuoka
    Hiroaki Matsuoka
  • KSKazuaki Shimamoto
    Kazuaki Shimamoto
  • KSKazuyuki Shimada
    Kazuyuki Shimada
  • YIYutaka Imai
    Yutaka Imai
  • KKKenjiro Kikuchi
    Kenjiro Kikuchi
  • TETanenao Eto
    Tanenao Eto
  • GKGenjiro Kimura
    Genjiro Kimura
  • TITsutomu Imaizumi
    Tsutomu Imaizumi

Abstract
In this prospective, randomized, open-label, blinded end point study, we aimed to establish whether strict blood pressure control (P =0.38). In summary, blood pressure targets of <140 mm Hg are safely achievable in relatively healthy patients ≥70 years of age with isolated systolic hypertension, although our trial was underpowered to definitively determine whether strict control was superior to less stringent blood pressure targets.

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