Recent Updates on Supramolecular‐Based Drug Delivery – Macrocycles and Supramolecular Gels
- 5 May 2022
- journal article
- review article
- Published by Wiley in The Chemical Record
- Vol. 22 (7) , e202200053
Abstract
Supramolecules‐based drug delivery has attracted significant recent research attention as it could enhance drug solubility, retention time, targeting, and stimuli responsiveness. Among the different supramolecules and assemblies, the macrocycles and the supramolecular hydrogels are the two important categories investigated to a greater extent. Here, we provide the most recent advancements in these categories. Under macrocycles, reports on drug delivery by cyclodextrins, cucurbiturils, calixarenes/pillararenes, crown ethers and porphyrins are detailed. The second category discusses the supramolecular hydrogels of macrocycles/polymers and low molecular weight gelators. The updated information provided could be helpful to advance R & D in this vital area.Keywords
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